Actos Users at Greater Risk for Bladder Cancer, Heart Failure

California Actos Bladder Cancer Lawyer

Actos has been linked to increased risk of bladder cancer and heart failure.

In addition to an increased risk of bladder cancer, Actos users may also be at greater risk for developing congestive heart failure.

According to a National Institutes of Health (NIH) report issued last year, patients taking Actos (pioglitazone) may be more likely to develop symptoms of congestive heart failure. For those patients who already have the disease, Actos use may worsen existing symptoms.

The NIH is warning Actos users about the signs and symptoms of congestive heart failure, which include:


  • Cough
  • Feeling of fatigue, weakness, faintness
  • Loss of appetite
  • Need to urinate at night
  • Irregular pulse
  • Heart palpitations
  • Shortness of breath when you are active or after you lie down
  • Enlarged liver or abdomen
  • Swelling of the legs or ankles
  • Weight gain

Actos was first approved by the FDA in 1999 to treat Type 2 diabetes in adult patients. The drug quickly became a best-seller for Japanese manufacturer Takeda Pharmaceuticals, generating nearly $5 billion in sales in 2010 alone. Problems with Actos first came to light in September 2010, after an FDA-sponsored research study indicated that patients who used pioglitazone for long periods of time had a higher risk of developing bladder cancer. In June 2011, the FDA issued an updated safety communication concerning Actos warning patients and physicians that taking the drug for one year or longer could significantly elevate an individual’s bladder cancer risk.

Following the FDA’s announcement, a flood of lawsuits have been filed against Takeda on behalf of patients and their families who say Actos caused bladder cancer, heart failure and other serious side effects. Claims have been filed in state and federal courts across the country and recent Bloomberg report estimated that the number will top 10,000.  In December 2011, a U.S. Judicial Panel on Multidistrict Litigation voted to consolidate all federal Actos lawsuits for pretrial proceedings in a Louisiana district court.

Actos users who experienced symptoms of heart failure or symptoms of bladder cancer, which include blood in the urine, painful urination and lower back pain, are being urged to contact an experienced personal injury attorney to discuss their legal rights. The Actos injury lawyers at Nadrich & Cohen LLP are now providing no-cost, no-obligation case evaluations to Actos users in all 50 states who believe they were injured by the drug.

If you or a loved one took Actos and was diagnosed with bladder cancer, heart failure or another serious condition, call our Injury Hotline at 1-800-722-0765 to speak with a member of our Actos legal team. Help is available 24 hours a day, 7 days a week and there is no fee unless we recover a judgment on your behalf. Time is limited to file a claim so don’t hesitate to call us today to find out how we can help.

The Nadrich & Cohen personal injury blogs are sponsored by Nadrich & Cohen, LLC. This blog features news stories, personal cases and analysis of current events, all of which are intended for illustrative purposes only. Each case is different, and legal authority is constantly changing and evolving. Therefore, nothing on this site should be viewed as a guarantee or prediction of a similar future outcome. The information on this site should not be treated as authoritative, and readers should always consult with legal counsel before making any important legal decisions. Lastly, Nadrich & Cohen, LLC is not responsible for any comments contributed by visitors to this website.

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3 Responses to “Actos Users at Greater Risk for Bladder Cancer, Heart Failure”

  1. Search Attorney
    22. Jan, 2012 at 10:38 pm #

    Thank you for this post! This has helped me so much!

  2. Find Lawyer
    24. Jan, 2012 at 7:33 pm #

    Good job on this website!

  3. DumnCrymn
    25. Jan, 2012 at 4:19 am #

    Hello! Just want to say thank you for this interesting article! =) Peace, Joy.

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